The effect of kihito extract granules in people with Alzheimer’s disease

The most prominent neurochemical change in patients with Alzheimer’s disease is a deficiency of choline acetyltransferase, the enzyme responsible for the synthesis of acetylcholine.

Polygalae radix is thought to be a useful component of kami-untan-to because it increases the activity of choline acetyltransferase. This study evaluated this Japanese herbal (kampo) medicine in people with Alzheimer’s disease. Continue reading The effect of kihito extract granules in people with Alzheimer’s disease →

Why new mums get depressed and what to do about it

Dr. Kathleen Kendall-Tackett is a health psychologist and a board certified lactation consultant from the University of New Hampshire in Durham. Her work focuses on family violence and perinatal health.

Here are her thoughts on postpartum depression. Continue reading Why new mums get depressed and what to do about it →

Ginkgo biloba vs nifedipine to treat Raynaud’s disease

Raynaud’s disease causes some areas of the body (fingers, toes, tip of the nose and ears) to feel numb and cool in response to cold temperatures or stress. During a Raynaud’s attack, the arteries become narrow and limit blood flow to affected areas.

During the American Academy of Family Physicians 2007 Annual Scientific Assembly Ginkgo biloba was reportedly less effective than the calcium channel blocker nifedipine (Adalat, Procardia). Continue reading Ginkgo biloba vs nifedipine to treat Raynaud’s disease →

Toxic metals and pesticides in the ayurvedic formulation, Dashmoola

Dashmoola is a popular herbal formulation in ayurvedic medicine. It’s used to reduce fever and modify the immune response.

In this study, scientists from the National Botanical Research Institute in Lucknow, India tested the roots and stems from 10 herbs used to prepare Dashmoola. Continue reading Toxic metals and pesticides in the ayurvedic formulation, Dashmoola →

Behavioral training and biofeedback to treat temporomandibular dysfunction

Temporomandibular joint (TMJ) dysfunction involves face pain, clicking sounds, and limited movement of the jaw. About 33% of the population has it; fewer need treatment.

This study suggests that cognitive behavioral therapy plus biofeedback is cost-effective treatment.

Continue reading Behavioral training and biofeedback to treat temporomandibular dysfunction →

Herbal supplements for weight loss: What works, what doesn’t

In preparation for the upcoming weight management conferences in Europe, here is what we know about the value of herbals as an aid to weight loss.

Continue reading Herbal supplements for weight loss: What works, what doesn’t →

Pomegranate juice doesn’t inhibit cytochrome P450 enzymes in humans

Several years ago a study in human liver tissue and in rats concluded that pomegranate juice inhibited CYP3A — a liver enzyme in the cytochrome P450 system important for metabolizing drugs. The implications were that — just as with grapefruit — people taking drugs such as statins for cholesterol might be exposed to much higher blood levels and greater risk of side effects.

We now find that when studied in healthy volunteers, pomegranate juice is not associated with this risk.

Continue reading Pomegranate juice doesn’t inhibit cytochrome P450 enzymes in humans →

Incorporating the JELIS results in cholesterol-lowering treatment plans

As summarized here, JELIS is the acronym for “Japan EPA Lipid Intervention Study.” It showed that adding eicosapentaenoic acid (EPA) — an active component of omega-3 fatty acids — to low-dose statin therapy lowered the risk for certain major problems involving the heart.

The results are finding their way into mainstream recommendations for hypercholesterolemia treatment. Continue reading Incorporating the JELIS results in cholesterol-lowering treatment plans →

Innovation in portion control to treat obesity

On a recent trip to Paris I was told that the reason there are no fat Parisian women is because they understand portion control in their diet. Restaurants in France serve smaller portions. Nobody complains because … well … they’re in Paris, after all.

Here’s a typical American approach to portion control, from Dr. Mary Ellen Camire and Megan Blackmore writing in the latest edition of Food Technology magazine.

Continue reading Innovation in portion control to treat obesity →

Complementary and Alternative Medicine: Fair, Balanced, and to the Point