Category Archives: Marijuana (Cannabinoids)

CAM and diabetes: An update of recent studies

The World Health Organization has predicted a 39% rise in the worldwide prevalence of diabetes by 2030. And an article in The Lancet indicates this might be an underestimation.

Since November is Diabetes Month, here’s a round-up of CAM options for people with diabetes from 2006 through March 2007.
Continue reading CAM and diabetes: An update of recent studies →

Cannabis use in hepatitis C

Cannabis use should be discouraged in patients with chronic hepatitis C (CHC), according to researchers in France.

First, the details.

  • 315 patients with untreated CHC and having a liver biopsy were studied.
  • Detailed histories of recent marijuana, alcohol, and tobacco use were recorded.
  • The biopsies were examined using METAVIR — a scoring system that gives an indication of the activity or amount of inflammation and amount of fibrosis or scarring in the liver.

And, the results.
There were 6 predictors of marked steatosis (accumulation of fat in the liver).

  • Daily cannabis users compared to occasional users and nonusers
  • Viral activity grade of the disease (greater or equal to A2)
  • Genotype 3 (one of the genetic variations and stains of hepatitis C)
  • Body mass index (BMI) greater than 27 kg/m2
  • High blood sugar levels or diabetes
  • HCV RNA load in the blood (associated with a worse outcome of disease) or alcohol intake (greater than 30 g/day)

The bottom line?
Steatosis is important because a build up of fat in the liver worsens liver damage and makes CHC harder to treat.

The authors concluded that daily cannabis smoking is a “predictor of steatosis severity during CHC.” And they recommend that “cannabis use should be discouraged in patients with CHC.”

Among the 6 predictors of steatosis reported in this study, marijuana use is a comparatively easy risk factor to modify and thereby reduce the severity of this disease.

7/6/08 11:05 JR

Debate: Don’t be fooled into legalizing marijuana

Earlier this year, a study published by researchers at Texas A&M Health Science Center concluded, “Consistent with other studies of the liberalization of cannabis laws, medical cannabis laws do not appear to increase use of the drug.”

Gee wiz. I guess that’s the end of that debate. Not really, as I debate the issue with a valued reader of this blog. Continue reading Debate: Don’t be fooled into legalizing marijuana →

Making a case for an endocannabinoid deficiency

Dr. Ethan Russo (no relation) is a consultant for GW Pharmaceuticals and a proponent of medical marijuana.

This article is the latest justification that “migraine, fibromyalgia, irritable bowel syndrome, and related conditions display common clinical, biochemical and pathophysiological patterns that suggest an underlying clinical endocannabinoid deficiency that may be suitably treated with cannabinoid medicines.” Continue reading Making a case for an endocannabinoid deficiency →

Periodontal disease in kids who smoke pot

Periodontal disease is a gum disease (such as periodontitis or gingivitis) that, if untreated, inflames and eventually destroys the bone and tissues that support and anchor the teeth.

Cannabis smoking is a risk factor for periodontal disease, according to this study published in the Journal of the American Medical Association. Continue reading Periodontal disease in kids who smoke pot →