The C.A.M. Report
Complementary and Alternative Medicine: Fair, Balanced, and to the Point
  • About this web log

    This blog ran from 2006 to 2016 and was intended as an objective and dispassionate source of information on the latest CAM research. Since my background is in pharmacy and allopathic medicine, I view all CAM as advancing through the development pipeline to eventually become integrated into mainstream medical practice. Some will succeed while others fail. But all are treated fairly here.

  • About the author

    John Russo, Jr., PharmD, is president of The MedCom Resource, Inc. Previously, he was senior vice president of medical communications at www.Vicus.com, a complementary and alternative medicine website.

  • Common sense considerations

    The material on this weblog is for informational purposes. It is not medical advice or counsel. Be smart, consult your health professional before using CAM.

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  • Recent Comments

    Cannabis drug fails in neuropathic pain due to MS

    GW Pharmaceuticals has announced that its major study of Sativex in 339 patients with central neuropathic pain due to multiple sclerosis (MS) failed to provide adequate pain relieve in patients who had failed conventional therapy previously.

    Sativex is a spray administered by mouth, which contains tetrahydrocannabinol (THC) and cannabidiol (CBD). Neuropathic pain is pain transmitted by a damaged nervous system. It occurs in about two-thirds of patients with MS, and often has a significant effect on their daily activities.

    There’s lots of spinning to try and explain why the drug failed.

    The R&D director of the company and the principal investigator are blaming “an abnormally high placebo response” and a flawed study design, which was supposed to reflect the “real world” use of Sativex whereby patients initially experiment with dosing of Sativex to find their optimum dose level and which, once established, is usually maintained thereafter.

    I think they should stop whining.

    These people were paid a lot of money to apply their expertise to designing a sound study. Either the drug doesn’t work better than placebo, or they failed their responsibility.

    Or both.

    4/20/08 15:13 JR

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