Category Archives: G. BOTANICALS

The goldenseal (berberine)/cyclosporine drug interaction

Goldenseal (Hydrastis canadensis) is promoted for a variety of uses. The active components are hydrastine and berberine. Both inhibit the liver metabolizing enzyme system known as cytochrome P450. Therefore, people treated the immunosuppressant, cyclosporine A (CsA; Sandimmune) and taking this herbal or berberine are at risk of a drug interaction.

Here’s what we know based on studies at the Wuhan General Hospital in Wuhan, China. Continue reading The goldenseal (berberine)/cyclosporine drug interaction →

Review of herbal medicines in gynecology

Dr. Cathi Dennehy from the Department of Clinical Pharmacy at the University of California San Francisco has reviewed the evidence.

I was surprised by her assessment of black cohosh for menopausal symptoms.

Here’s a summary of her findings.

Continue reading Review of herbal medicines in gynecology →