Category Archives: G. BOTANICALS

Saw palmetto withdrawn from the market in Denmark

In February, the Danish Ministry for Family and Consumer Affairs withdrew food supplements containing saw palmetto because of concerns about its effect on the hormone system coupled with a lack of data about its safety in long-term use.

Dr. Kirsten Pilegaard, PhD, senior advisor for the Danish Institute for Food and Veterinary Research stated, “On the basis of the information available, it is not possible to establish a dose that does not give rise to concern.”

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Ayurvedic drug reported effective to treat osteoarthritis of the knee

RA-11 (Artrex, Mendar) is a standardized multiplant Ayurvedic drug that contains Withania somnifera, Boswellia serrata, Zingiber officinale, and Curcuma longa. In a 32-week study of 90 people with osteoarthritis of the knee, it was more effective than placebo for pain relief.

OK, but I have some questions.

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St. John’s wort for depression

A review article published in 2001 identified 8 clinical studies in which St. John’s wort was more effective than placebo in treating mild to moderate depression. “The absolute increased response rate with the use of St. John’s wort ranged from 23% to 55% higher than with placebo, but ranged from 6% to 18% lower compared with tricyclic antidepressants.”

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Effects of policosanol in patients with ischemic stroke

This blog has chronicled the lipid-lowering effects of policosanol, which lowers LDL (bad) cholesterol levels by 20% to 30%. Its mechanism of action differs from statins. However, it’s close enough that for safety, I would be cautious taking policosanol and a statin at the same time. One-A-Day Cholesterol Plus contains policosanol.

Now, a new study reports that policosanol has a positive effect on recovery in patients with ischemic stroke. This might be an overstatement, but let’s take a closer look.

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Black cohosh: The new bad boy of supplements

Every time I turn around, another agency is warning its constituents to beware of black cohosh.

Japan’s Ministry of Health, Labour and Welfare has now issued a warning to Japanese users of black cohosh. While there are no actual examples of the herb causing health problems in Japan, care should be exercised regarding its intake.

The risk of liver toxicity with black cohosh was reviewed here in an earlier post.

9/26/06 21:08 JR

Horse chestnuts to treat chronic venous insufficiency

When your leg veins can’t pump enough blood back to your heart, you have chronic venous insufficiency (CVI). Today, standardized horse chestnut seed extract (HCSE) is a well-established treatment for CVI and edema. It’s a common ingredient in lotions, creams, massage oils, and other skin care products, often in combination with other herbal ingredients.

How does it work?

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Herbal interactions with immunosuppressive drugs

Dr. James Beaulieu, a clinical pharmacist specialist at Rhode Island Hospital in Providence, has published an excellent review of this topic.

If you are receiving immunosuppressive treatments and taking or considering taking any herbal medicine, consult this article first.

Immunosuppressive therapy is used for the following reasons.

  • Prevent rejection of transplanted organs and tissues (eg, bone marrow, heart, kidney, liver)
  • Treat autoimmune diseases or diseases that are most likely of autoimmune origin (eg, rheumatoid arthritis, myasthenia gravis, systemic lupus erythematosus, Crohn’s disease, and ulcerative colitis)

A list and overview of immunosuppressive drugs are available here.

9/24/06 11:18 JR

Might aromatherapy massage improve sleep in children with autism?

In an earlier post it was concluded that lavender oil treatments might be helpful for treating insomnia in adults. Children with autism often have sleep difficulties. But this latest study suggests it does not appear that their sleep patterns are altered by this treatment.

Here are the details of the study. Do you agree with the conclusions?
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Lavender oil treatment for insomnia

The National Center for Complementary and Alternative Medicine has published a survey on the extent of insomnia and use of CAM in Americans. WebMD summarizes the findings here.

  • 35 million adults regularly had insomnia in 2002
  • 1.6 million of them tried CAM to get some sleep

Most often they used herbs and vitamins, or mind-body therapies. Most CAM treatments for insomnia are not well studied, although two studies of inhaled lavender oil have been published, and are reviewed here.

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Butterbur root for allergic rhinitis: More good news

In an earlier post, the effectiveness of butterbur (Ze 339) was reviewed and found to be as effective as the antihistamines, citirizine (Zyrtec) and fexofenadine (Allegra) to treat the runny nose; sneezing; congestion; and irritation in the nose, eyes, throat, and ears associated with allergic rhinitis.

Now, here are the results of a survey of 580 patients with seasonal allergic rhinitis treated with an average of 2 tablets of Ze 339 daily for 2 weeks.

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