Category Archives: THINGS THAT DON’T FIT ABOVE

Dietary supplements, allopathic, and homeopathic medicines

An article published by John Borneman and Robert Field on the Hyland’s website (and here) provides insight to the regulatory differences between these drug categories in the US.

It’s instructive to appreciate the similarities and differences. The authors believe the guidelines for homeopathic medicine could serves as a model for approval and postmarketing oversight of dietary supplements. Continue reading Dietary supplements, allopathic, and homeopathic medicines →

Update: Grapefruit juice:Rx drug interactions

According to Dr. William McCloskey, the likelihood of drug:grapefruit juice interactions having a negative effect on a patient’s response to the drug has not been clearly established.

This might be due to the fact that many drugs affected by grapefruit juice have a wide therapeutic index. In other words, toxic blood levels are so much higher than the blood levels needed to achieve an effective treatment dose that any increase caused by grapefruit juice is not sufficient to reach toxicity.

That’s not to say there is no risk of a grapefruit juice:drug interaction.

Unfortunately, the source article has been deleted, but here’s the bottom line. If you take any of the drugs listed below and feel you must drink grapefruit juice, first discuss it with your doctor.

  • Amiodarone (Cordarone)
  • Atorvastatin (Lipitor)
  • Buspirone (Buspar)
  • Carbamazepine (Tegretol)
  • Clomipramine (Anafranil)
  • Cyclosporine (Sandimmune, Neoral)
  • Diazepam (Valium)
  • Etoposide (VePesid)
  • Felodipine (Plendil)
  • Fexofenadine (Allegra)
  • Itraconazole (Sporanox)
  • Lovastatin (Mevacor)
  • Methadone (Methadose)
  • Midazolam (Versed)
  • Nicardipine (Cardene)
  • Nifedipine (Procardia)
  • Nimodipine (Nimotop)
  • Nisoldipine (Sular)
  • Saquinavir (Invirase)
  • Sildenafil (Viagra)
  • Simvastatin (Zocor)
  • Triazolam (Halcion)

3/19/08 11:13 JR

Cost-effectiveness of music therapy in palliative care

Reminiscence music reportedly reduces the symptoms of depression in patients with dementia. It’s also effective for agitation and disruptive behavior in patients with dementia, and makes it easier to provide care.

Now, researchers from the Kaiser Foundation Hospital in Santa Clara, California report that music therapy makes fiscal sense as well. Continue reading Cost-effectiveness of music therapy in palliative care →

Improved quality of acupuncture studies

First published in 1966, CONSORT (CONsolidated Standards of Reporting Trials) is intended to improve the reporting of medical research. Authors use it as a checklist when they submit articles for publication. By standardizing the information that must appear in a research article, this should help assure that the studies are well designed and the results are useful to readers.

Has it helped improve acupuncture studies? Continue reading Improved quality of acupuncture studies →

Which brands of herbals and supplements should you trust?

Dr. Tod Cooperman, who is president of the third-party product analysis company, ConsumerLab, states that one in 4 products tested by his company is problematic in one way or another, and more than half of multivitamins tested do not meet what is printed on the labels.

So, which companies reliably provide quality products? Continue reading Which brands of herbals and supplements should you trust? →

How long does it take to get a CAM to market?

In a previous post I quoted from a Chinese medicine website that proclaimed “after sifting through more than 1,000 plants for 13 years, the researchers found 150 herbs with medicinal properties that appeared active in fighting HIV … From there, they selected the bark from white mulberry roots and four other Chinese plants as basic elements of their compound drug.” Continue reading How long does it take to get a CAM to market? →

Medical students in Wales want more education on CAM

In 2000, the House of Lords Select Committee’s Report on CAM recommended familiarization with CAM for medical students and doctors.

According to this article, little has been done. But it confirms an interest in greater exposure to CAM education among medical students in Wales. Continue reading Medical students in Wales want more education on CAM →