Category Archives: Diet-Nutrition

Update: Grapefruit juice:Rx drug interactions

According to Dr. William McCloskey, the likelihood of drug:grapefruit juice interactions having a negative effect on a patient’s response to the drug has not been clearly established.

This might be due to the fact that many drugs affected by grapefruit juice have a wide therapeutic index. In other words, toxic blood levels are so much higher than the blood levels needed to achieve an effective treatment dose that any increase caused by grapefruit juice is not sufficient to reach toxicity.

That’s not to say there is no risk of a grapefruit juice:drug interaction.

Unfortunately, the source article has been deleted, but here’s the bottom line. If you take any of the drugs listed below and feel you must drink grapefruit juice, first discuss it with your doctor.

  • Amiodarone (Cordarone)
  • Atorvastatin (Lipitor)
  • Buspirone (Buspar)
  • Carbamazepine (Tegretol)
  • Clomipramine (Anafranil)
  • Cyclosporine (Sandimmune, Neoral)
  • Diazepam (Valium)
  • Etoposide (VePesid)
  • Felodipine (Plendil)
  • Fexofenadine (Allegra)
  • Itraconazole (Sporanox)
  • Lovastatin (Mevacor)
  • Methadone (Methadose)
  • Midazolam (Versed)
  • Nicardipine (Cardene)
  • Nifedipine (Procardia)
  • Nimodipine (Nimotop)
  • Nisoldipine (Sular)
  • Saquinavir (Invirase)
  • Sildenafil (Viagra)
  • Simvastatin (Zocor)
  • Triazolam (Halcion)

3/19/08 11:13 JR

An academic allopathic view of CAM options for arthritic pain

Arthritis pain includes a range of ailments, from acute musculoskeletal injuries to degenerative osteoarthritis (OA) to chronic inflammatory conditions, such as rheumatoid arthritis.

Dr. Eric Ruderman, Associate Professor of Medicine in the Division of Rheumatology at Northwestern University Feinberg School of Medicine in Chicago has published a review on Medscape, with lots of space devoted to CAM: exercise, acupuncture, and nutritional supplements. Continue reading An academic allopathic view of CAM options for arthritic pain →

The pros and cons of folic acid fortification of foods

Fortifying food, such as wheat and corn flour, with folic acid reduces the risk of spina bifida in babies.

This public health practice was introduced 10 years ago in North America. Now, that practice is being debated in the UK and worldwide. “Are the benefits to the few outweighed by possible harm to some of the many exposed? Continue reading The pros and cons of folic acid fortification of foods →

Vitamin E supplements and the risk of lung cancer

A recent review of the medical literature revealed that except for prostate cancer, there was no evidence that vitamin E could protect from getting lung, stomach, esophageal, pancreatic, breast, or thyroid cancer.

Now, this study by researchers at the University of Washington in Seattle reports negative news for the vitamin E supplements and lung cancer. Continue reading Vitamin E supplements and the risk of lung cancer →

Are Canadian academics opposed to organic farming?

Earlier this year a report from the University of Alberta concluded that the environmental impact of food-miles racked up by organic produce when making the trip from farm to grocery store cancels out the benefits of growing it according to organic principals.

Now, there’s this from a technician at Malaspina University College in British Columbia, Canada. Continue reading Are Canadian academics opposed to organic farming? →

A ten-year perspective: The influence of nutrition on prostate cancer

Ten years ago, the late Dr. William Fair, a surgeon at the Memorial Sloan-Kettering Cancer Center and CAM advocate wrote, “epidemiologic and laboratory evidence increasingly demonstrate that nutritional factors, especially reduced fat intake, soy proteins, vitamin E derivatives, and selenium, may have a protective effect against prostate cancer.”

Now, Steffen Theobald, a nutritional consultant and manager at the Scientific Association for the Improvement of Patient Competence in Germany updates the role of nutrition in the development, prevention, and treatment of prostate cancer.

Continue reading A ten-year perspective: The influence of nutrition on prostate cancer →