The C.A.M. Report
Complementary and Alternative Medicine: Fair, Balanced, and to the Point
  • About this web log

    This blog ran from 2006 to 2016 and was intended as an objective and dispassionate source of information on the latest CAM research. Since my background is in pharmacy and allopathic medicine, I view all CAM as advancing through the development pipeline to eventually become integrated into mainstream medical practice. Some will succeed while others fail. But all are treated fairly here.

  • About the author

    John Russo, Jr., PharmD, is president of The MedCom Resource, Inc. Previously, he was senior vice president of medical communications at, a complementary and alternative medicine website.

  • Common sense considerations

    The material on this weblog is for informational purposes. It is not medical advice or counsel. Be smart, consult your health professional before using CAM.

  • Recent Posts

  • Recent Comments

    Is it possible to prevent prostate cancer with diet and supplements?

    Researchers at Fred Hutchinson Cancer Research Center, in Seattle, Washington, reviewed the evidence.

    First, the details.

    • Nutritional risk factors for prostate cancer among 9,559 participants in the Prostate Cancer Prevention Trial were reviewed.
    • The presence of cancer was determined by prostate biopsy, which was recommended because of an elevated prostate-specific antigen level or an abnormal digital rectal examination.
    • The biopsy was offered to all men at the end of the study.
    • Nutrient intake was assessed using a food frequency questionnaire and a structured supplement-use questionnaire.

    And, the results.

    • Cancer was detected in 1,703 men.
    • No nutrients or supplements were associated with prostate cancer risk.
    • Risk of high-grade (aggressive) cancer was associated with high intake of polyunsaturated fats.
    • Intake of more dietary calcium was associated with a greater chance of low-grade (less aggressive) cancer vs high-grade cancer.
    • Intake of lycopene, long-chain omega-3 fatty acids, vitamin D, vitamin E, and selenium, were not associated with the risk of cancer.
    • High intake of omega-6 fatty acids may increase prostate cancer risk because of their effects on inflammation and oxidative stress.

    The bottom line?

    There seem to be 2 take-away points from this review.

    First, there’s no evidence that dietary or supplemental intake of nutrients often proposed to prevent prostate cancer, including lycopene, omega-3 fatty acids, vitamin D, vitamin E, and selenium, was associated with risk of low- or high-grade cancer.

    Second, polyunsaturated fat was associated with increased risk of high-grade prostate cancer. This suggests that more research into inflammation and other metabolic processes affected by these fats may be important in understanding prostate cancer etiology.

    9/24/10 21:35 JR

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