Category Archives: Coenzyme Q10

Coenzyme Q10: Two points of view

It’s always a good idea to get a second opinion when it comes to your healthcare. Coenzyme Q10 (CoQ10) has been used, recommended, or studied for many conditions, but its use is controversial. Here are two websites that reviewed the literature and are ready to advise on the status of CoQ10 — MotherNature.com (MN) and MayoClinic.com (MC).

Here are comparative evaluations and ratings for three sample diseases.

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CAM for heart disease: Current state of the evidence

During a seminar at the American Heart Association 2006 meeting titled “The Science Behind Popular Nutrition Claims,” medical researchers summarized the research on a number of complementary options to “help maintain a healthy heart.”

Here is a summary of the Medscape article. Links to more info are highlighted.

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How policosanol lowers cholesterol and implications for your safety

In a previous post I reviewed policosanol, which can lower LDL (bad) cholesterol levels by 20% to 30%.

The source of policosanol seems to influence its activity, with Cuban sugar cane-based policosanol being most effective. It’s available on the Internet and in stores. In fact, One-A-Day Cholesterol Plus contains sugar cane-based policosanol.

Now, a study conducted at the University of Kentucky College of Pharmacy shows how it works.

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What is the correct dose of coenzyme Q10?

There is no well-established dose of coenzyme Q10. One review listed a range of doses from 75 mg to 360 mg per day to treat high blood pressure. And the suggested doses for other conditions fall within this range.

In Japan, the medicinal dosage of CoQ10 is 30 mg/day, but it’s more commonly taken as a dietary supplement at 100 mg to 200 mg daily.

For the past year Japan’s Ministry of Health, Labour and Welfare has worked to get control of this situation. In the absence of sufficient dosing data, the following actions are likely to be implemented.

  • Require manufacturers and distributors to confirm the safety of the dose in long-term use
  • Provide consumers with relevant warnings or cautions
  • Document information on adverse reactions, etc.

Good work.

8/22/06 18:59 JR

CAM options to treat Alzheimer’s disease

Several herbal remedies and other dietary supplements are promoted as effective treatments for Alzheimer’s disease and related disorders. The Alzheimer’s Association summarizes the supporting data for the following treatments.

  • Coenzyme Q10
  • Ginkgo biloba
  • Huperzine A
  • Phosphatidylserine
  • Coral calcium

A review of ginkgo biloba is also available here.

Illustration: Neurofibrillary tangles and fiberlike processes of neurons (black) surround an amyloid plaque. Source: Chemical and Engineering News

7/8/06 15:50 JR