The C.A.M. Report
Complementary and Alternative Medicine: Fair, Balanced, and to the Point
  • About this web log

    This blog ran from 2006 to 2016 and was intended as an objective and dispassionate source of information on the latest CAM research. Since my background is in pharmacy and allopathic medicine, I view all CAM as advancing through the development pipeline to eventually become integrated into mainstream medical practice. Some will succeed while others fail. But all are treated fairly here.

  • About the author

    John Russo, Jr., PharmD, is president of The MedCom Resource, Inc. Previously, he was senior vice president of medical communications at, a complementary and alternative medicine website.

  • Common sense considerations

    The material on this weblog is for informational purposes. It is not medical advice or counsel. Be smart, consult your health professional before using CAM.

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    Review: Supplemental calcium to prevent colorectal cancer

    Researchers at the University of Sheffield, in the UK, reviewed the evidence for calcium in reducing the recurrence of adenomas (benign tumors) and the occurrence of colorectal cancer.

    First, the details.

    • The researchers identified 3835 citations, of which 6 studies (8 papers) were included in the review.

    And, the results.

    • Familial adenomatous polyposis (FAP)
      • Supplemental calcium had no effect on the number of adenomas in 1 small study.
        • FAP is an inherited disorder characterized by cancer of the large intestine (colon) and rectum.
    • People with a history of adenomas
      • Data from 3 studies were combined for a meta-analysis that reported a significant reduction in the risk for adenoma recurrence among those receiving calcium 1200 to 2000 mg/day.
    • Advanced adenoma
      • No effect of calcium supplementation was seen.
    • People not at increased risk for colorectal cancer
      • Meta-analysis of data from 2 studies suggested that calcium, with or without vitamin D, had no effect on risk.

    The bottom line?

    The authors concluded, “Supplemental calcium was effective for the prevention of adenoma recurrence in populations with a history of adenomas, but no similar effect was apparent in populations at higher or lower risk.”

    6/28/10 18:09 JR

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