The C.A.M. Report
Complementary and Alternative Medicine: Fair, Balanced, and to the Point
  • About this web log

    This blog ran from 2006 to 2016 and was intended as an objective and dispassionate source of information on the latest CAM research. Since my background is in pharmacy and allopathic medicine, I view all CAM as advancing through the development pipeline to eventually become integrated into mainstream medical practice. Some will succeed while others fail. But all are treated fairly here.

  • About the author

    John Russo, Jr., PharmD, is president of The MedCom Resource, Inc. Previously, he was senior vice president of medical communications at www.Vicus.com, a complementary and alternative medicine website.

  • Common sense considerations

    The material on this weblog is for informational purposes. It is not medical advice or counsel. Be smart, consult your health professional before using CAM.

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    Beneficial effects of OJ on blood vessels and blood pressure

    Studies show benefits of some polyphenol-rich foods on several markers for cardiovascular diseases.

    Researchers at Centre Clermont-Ferrand–Theix, in France, studied whether these effects might be related to hesperidin, the major polyphenol of the orange juice.

    First, the details.

    • 24 healthy overweight adult men received each treatment at different times — crossover study — for 4 weeks each.
      • Orange juice 500 mL
      • Hesperidin + 500 mL control drink
      • Placebo + 500 mL control drink

    And, the results.

    • Diastolic blood pressure was significantly lower after orange juice or hesperidin than after consumption of placebo.
    • Microvascular endothelium-related reactivity (the small blood vessels that feed the heart) was not significantly affected when measured after an overnight fast.
    • Orange juice and hesperidin significantly improved postprandial microvascular endothelial reactivity vs placebo when measured at the peak blood levels of hesperidin.

    The bottom line?

    The authors concluded, “Hesperidin could be causally linked to the beneficial effect of orange juice.”

    These results support the results from an earlier study in animals.

    The study was supported by a grant from the Florida Department of Citrus.

    12/15/10 22:23 JR

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