The C.A.M. Report
Complementary and Alternative Medicine: Fair, Balanced, and to the Point
  • About this web log

    This blog ran from 2006 to 2016 and was intended as an objective and dispassionate source of information on the latest CAM research. Since my background is in pharmacy and allopathic medicine, I view all CAM as advancing through the development pipeline to eventually become integrated into mainstream medical practice. Some will succeed while others fail. But all are treated fairly here.

  • About the author

    John Russo, Jr., PharmD, is president of The MedCom Resource, Inc. Previously, he was senior vice president of medical communications at www.Vicus.com, a complementary and alternative medicine website.

  • Common sense considerations

    The material on this weblog is for informational purposes. It is not medical advice or counsel. Be smart, consult your health professional before using CAM.

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    Relationship between Vitamin D deficiency and kidney disease in blacks

    vitamindLow blood levels of vitamin D may account for much of the increased risk for end stage kidney disease among black individuals, according to this study by researchers in the US.

    First, the details.

    • Medicare claims files for 13,328 people were reviewed for measurements of 25(OH)D and end stage kidney disease — a progressive loss of kidney function over a period of months or years.

    And, the results.

    • 34% of non-Hispanic black individuals had vitamin D blood levels less than 15 ng/mL compared with 5% of non-Hispanic white individuals — a significant difference.
    • During about 9 years, 65 participants developed end stage kidney disease.
    • After adjusting for demographic, socioeconomic, and clinical and laboratory factors (including diabetes, high blood pressure, estimated kidney function, and albumin in the urine), participants with vitamin D blood levels less than 15 ng/mL were at 2.6 time greater risk of end stage kidney disease than those with levels at least 15 ng/mL — a significant difference.
    • After adjustment for the effects of potentially confounding factors, non-Hispanic black individuals had a 2.83-fold higher risk for developing ESRD compared with non-Hispanic white individuals.
    • Additional adjustment for 25(OH)D levels reduced the risk by 58%.

    The bottom line?
    The authors concluded, “Low 25(OH)D levels [are] associate with development of end stage kidney disease even after adjustment for multiple risk factors. Low 25(OH)D levels may account for a substantial proportion of the increased risk for ESRD experienced by black individuals.”

    Since the study was conducted in a relatively small number of people, the authors recommended that more research is warranted.

    10/30/09 23:01 JR

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