The C.A.M. Report
Complementary and Alternative Medicine: Fair, Balanced, and to the Point
  • About this web log

    This blog ran from 2006 to 2016 and was intended as an objective and dispassionate source of information on the latest CAM research. Since my background is in pharmacy and allopathic medicine, I view all CAM as advancing through the development pipeline to eventually become integrated into mainstream medical practice. Some will succeed while others fail. But all are treated fairly here.

  • About the author

    John Russo, Jr., PharmD, is president of The MedCom Resource, Inc. Previously, he was senior vice president of medical communications at, a complementary and alternative medicine website.

  • Common sense considerations

    The material on this weblog is for informational purposes. It is not medical advice or counsel. Be smart, consult your health professional before using CAM.

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    Safety of vitamin D during pregnancy

    Researchers at the Medical University of South Carolina in Charleston, studied healthy expectant mothers.

    First, the details.

    • 494 women at 12-16 weeks’ gestation received 400, 2000 or 4000 IU vitamin D(3) /day until delivery.
    • Maternal and neonatal circulating 25(OH)D at delivery were measured.

    And, the results.

    • The average blood levels of 25(OH)D at delivery and 1-month before delivery were significantly different among the groups.
    • The percent that achieved sufficient levels was significantly different by group — greatest in 4000 IU group.
    • Circulating levels of 25(OH)D had a significant and direct influence on circulating 1,25(OH)(2) D concentrations throughout pregnancy.
    • There were no differences between groups on any safety measure.
    • No side effects attributed to vitamin D supplementation or circulating 25(OH)D levels were reported.

    The bottom line?

    The authors concluded, “Vitamin D supplementation of 4,000 IU/day for pregnant women was safe and most effective in achieving sufficiency in all women and their neonates regardless of race.”

    More on this study is summarized here.

    6/28/11 22:29 JR

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