The C.A.M. Report
Complementary and Alternative Medicine: Fair, Balanced, and to the Point
  • About this web log

    This blog ran from 2006 to 2016 and was intended as an objective and dispassionate source of information on the latest CAM research. Since my background is in pharmacy and allopathic medicine, I view all CAM as advancing through the development pipeline to eventually become integrated into mainstream medical practice. Some will succeed while others fail. But all are treated fairly here.

  • About the author

    John Russo, Jr., PharmD, is president of The MedCom Resource, Inc. Previously, he was senior vice president of medical communications at, a complementary and alternative medicine website.

  • Common sense considerations

    The material on this weblog is for informational purposes. It is not medical advice or counsel. Be smart, consult your health professional before using CAM.

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    Calcium, probiotics, and cholesterol metabolism

    Researchers at Friedrich Schiller University, in Jena, Germany, studied the influence of a probiotic supplement alone and combined with a calcium supplement on lowering blood cholesterol levels.

    First, the details.

    • 32 men and women were assigned to drink a probiotic drink containing 1010 CFU/day Lactobacillus paracasei (LPC37) for 4 weeks.
    • Then, 1 group consumed bread enriched with pentacalcium (CaP) hydroxy-triphosphate (1 gram Ca/day).
    • The other group ate bread without CaP.
    • After 2 weeks of no treatment and another 2 weeks of taking placebo, the treatments were switched for another 4 weeks.
    • Neither the patients nor researchers knew the treatment given — double blind.

    And, the results.

    • After taking with LPC37 + CaP, total cholesterol and LDL (bad) cholesterol concentrations decreased significantly compared to LPC37 + placebo.
    • Fecal concentration of L.┬áparacasei and that of all lactobacilli increased significantly after LPC37 + CaP and LPC37 compared to placebo.
    • Secondary bile acids in feces increased significantly after LPC37 + CaP compared to placebo.

    The bottom line?

    A bit confusing, but in the end the authors concluded the following.

    • CaP influences the colonization of LPC37 in the human gut under.
    • The combined supplementation also decreases LDL-cholesterol and the LDL/HDL ratio in healthy men and women with moderately raised cholesterol.
      • This could be also due to the CaP supplementation.

    Probably no direct application at this time, but it might be important in the future.

    11/8/11 19:45 JR

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