The C.A.M. Report
Complementary and Alternative Medicine: Fair, Balanced, and to the Point
  • About this web log

    This blog ran from 2006 to 2016 and was intended as an objective and dispassionate source of information on the latest CAM research. Since my background is in pharmacy and allopathic medicine, I view all CAM as advancing through the development pipeline to eventually become integrated into mainstream medical practice. Some will succeed while others fail. But all are treated fairly here.

  • About the author

    John Russo, Jr., PharmD, is president of The MedCom Resource, Inc. Previously, he was senior vice president of medical communications at, a complementary and alternative medicine website.

  • Common sense considerations

    The material on this weblog is for informational purposes. It is not medical advice or counsel. Be smart, consult your health professional before using CAM.

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  • Recent Comments

    Marijuana interaction with warfarin reported

    Researchers from the Cheyenne Veterans Affairs Medical Center, in Wyoming report that when taken together, 1 patient experienced bleeding from the blood “thinner” warfarin (Coumadin).

    First, the details.

    • A 56-year-old man had been treated with warfarin for 11 years after heart valve replacement.
    • He came to the hospital with upper gastrointestinal bleeding.
    • His INR value was very high at 10.41, and his hemoglobin level was low at 6.6 g/dL.
      • The INR test measures the ability of blood clot: normal is 0.8 to 1.2.
      • A normal hemoglobin count is 14-17 g/dL for men.
    • He was treated to control his blood loss and left the hospital after 7 days.
    • 15 days later he returned with a constant nosebleed and increased bruising.
    • His INR value was even higher at 11.55.
    • Again, he was treated.
    • It was learned that the patient smoked marijuana more frequently throughout the period of these 2 hospitalizations due to depression.
    • He was counseled about the potential interaction of warfarin and marijuana.
    • He stopped smoking pot, and during the next 9 months his INR values ranged from 1.08 to 4.40 with no significant bleeding complications.

    The bottom line?
    This is the first reported case of a warfarin-marijuana interaction. More clinical reports would be useful to confirm this interaction.

    A PubMed search since this research was published revealed nothing new on this topic.

    6/17/09 19:08 JR; 2/3/11 21:52 JR

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