The C.A.M. Report
Complementary and Alternative Medicine: Fair, Balanced, and to the Point
  • About this web log

    This blog ran from 2006 to 2016 and was intended as an objective and dispassionate source of information on the latest CAM research. Since my background is in pharmacy and allopathic medicine, I view all CAM as advancing through the development pipeline to eventually become integrated into mainstream medical practice. Some will succeed while others fail. But all are treated fairly here.

  • About the author

    John Russo, Jr., PharmD, is president of The MedCom Resource, Inc. Previously, he was senior vice president of medical communications at, a complementary and alternative medicine website.

  • Common sense considerations

    The material on this weblog is for informational purposes. It is not medical advice or counsel. Be smart, consult your health professional before using CAM.

  • Recent Posts

  • Recent Comments

    Vitamins C, D, and mood disturbance in hospitalized patients

    Low blood levels of vitamins C and D are prevalent in acutely hospitalized patients.

    Researchers at McGill University, and Jewish General Hospital, in Montreal, Quebec, looked for a change in mood after raising blood levels of these vitamins.

    First, the details.

    • 55 patients were assigned to a treatment group.
      • Vitamin C 500 mg twice daily
      • Vitamin D 1000 IU twice daily
    • Changes in mood were assessed using the Profile of Mood States.
    • Neither the patients nor researchers knew the treatment given — double blind.

    And, the results.

    • 32 patients completed the study.
    • Vitamin C therapy significantly increased vitamin C levels in blood.
      • This was associated with a significant 34% reduction in mood disturbance.
    • Vitamin D therapy significantly increased 25-hydroxyvitamin D blood concentrations.
      • But this was not accompanied by a significant effect on mood.

    The bottom line?

    Despite the absence of a placebo control group, the authors concluded, “Treatment of hypovitaminosis C improves the mood state of acutely hospitalized patients.”

    10/8/10 20:21 JR

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