The C.A.M. Report
Complementary and Alternative Medicine: Fair, Balanced, and to the Point
  • About this web log

    This blog ran from 2006 to 2016 and was intended as an objective and dispassionate source of information on the latest CAM research. Since my background is in pharmacy and allopathic medicine, I view all CAM as advancing through the development pipeline to eventually become integrated into mainstream medical practice. Some will succeed while others fail. But all are treated fairly here.

  • About the author

    John Russo, Jr., PharmD, is president of The MedCom Resource, Inc. Previously, he was senior vice president of medical communications at, a complementary and alternative medicine website.

  • Common sense considerations

    The material on this weblog is for informational purposes. It is not medical advice or counsel. Be smart, consult your health professional before using CAM.

  • Recent Posts

  • Recent Comments

    Review of CAM for behavioral health

    Evidence for CAM to treat depression, anxiety, sleep disorders, and attention-deficit/hyperactivity disorder (ADHD) has been reviewed by researchers at Louisiana State University Health Sciences Center, in Kenner.

    Here’s what we know.


    • St. John’s wort
      • Strong evidence supports its use.
    • Omega-3 fatty acids and S-adenosyl-l-methionine
      • Growing support as potential adjuncts to conventional therapies.
    • Dehydroepiandrosterone, inositol, folate, and saffron
      • Evidence is insufficient to support an antidepressant benefit.


    • Kava
      • High-quality supporting evidence.
      • But its use is discouraged because of safety concerns over its potential to cause liver toxicity and drug interactions.
    • Valerian and inositol
      • Preliminary evidence supports their use.
    • St. John’s wort and passionflower
      • Little research support.

    Jet lag, or shift work

    • Melatonin
      • Likely to be useful.
    • Valerian
      • Little evidence of benefit.


    • No evidence supports CAM

    The bottom line?

    It’s useful to stop for a moment and take stock of the state of CAM research. However, there are differences of opinion on some of these topics.

    For example, earlier this year, researchers from Duke University in North Carolina reviewed the evidence and concluded “Available data suggest that melatonin is a well-tolerated and efficacious treatment option for pediatric patients with chronic sleep-onset insomnia and ADHD.”

    5/25/10 11:27 JR

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