Heart DiseaseOmega-3 Fatty Acids

Effect of omega-3 in patients with cardiomyopathy

 Researchers at the University of Brescia in Italy studied the effects of omega-3 fatty acids in patients with idiopathic dilated cardiomyopathy and frequent or repetitive ventricular arrhythmias.

Cardiomyopathy is a disease of the heart muscle. These patients are often at risk for arrhythmias (abnormal heart rhythms) or sudden death due to heart dysfunction.

First, the details.

  • 44 patients with idiopathic dilated cardiomyopathy and frequent or repetitive ventricular arrhythmias were randomly assigned to take placebo or omega-3 fatty acids.
  • Heart rate and rhythm was monitored continuously for 6 months.
  • Neither the researchers nor the patients knew their treatment — double-blind.

And, the results.

  • Based on a battery of tests, the risk of an arrhythmia  improved significantly with omega-3 treatment compared to placebo.
  • The ratio of omega-6 to omega-3 fatty acids in the blood decreased from 12 to 3 after taking omega-3 fatty acids.

The bottom line?
The authors concluded, “Omega-3 fatty acid administration is associated with favorable effects on parameters related to arrhythmic risk in patients with idiopathic dilated cardiomyopathy.”

In a separate study, researchers from the Royal Adelaide Hospital in Australia reported that in their patients, “Dietary omega-3 fatty acid supplementation decreased the inducibility of ventricular tachycardia in patients at risk of sudden cardiac death.”

“These findings suggest that dietary fish oil can have an antiarrhythmic effect.”

3/5/09 21:17 JR

Hi, I’m JR

John Russo, Jr., PharmD, is president of The MedCom Resource, Inc. Previously, he was senior vice president of medical communications at www.Vicus.com, a complementary and alternative medicine website.