The C.A.M. Report
Complementary and Alternative Medicine: Fair, Balanced, and to the Point
  • About this web log

    This blog ran from 2006 to 2016 and was intended as an objective and dispassionate source of information on the latest CAM research. Since my background is in pharmacy and allopathic medicine, I view all CAM as advancing through the development pipeline to eventually become integrated into mainstream medical practice. Some will succeed while others fail. But all are treated fairly here.

  • About the author

    John Russo, Jr., PharmD, is president of The MedCom Resource, Inc. Previously, he was senior vice president of medical communications at, a complementary and alternative medicine website.

  • Common sense considerations

    The material on this weblog is for informational purposes. It is not medical advice or counsel. Be smart, consult your health professional before using CAM.

  • Recent Posts

  • Recent Comments

    Drug-supplement interactions in perspective

    Researchers from the Mayo Clinic in Rochester, Minnesota have reviewed the evidence and report that most interactions are confined to a relatively small number of drug classes and supplements.

    First, the details.

    • 1818 patients treated at the Mayo Clinic in 6 different specialty clinics were surveyed for their use of dietary supplements.
    • Concurrent use of prescription drugs was obtained from patients’ medical records.
    • A computerized search was used to assess the potential significance of each interaction on the patients’ health.

    And, the results.

    • 710 (40%) of the 1795 patients who responded reported use of dietary supplements.
    • 107 interactions with potential clinical significance were identified.
    • The 5 most common natural products with a potential for interaction accounted for 68% of the potential clinically significant interactions.
      • Garlic
      • Valerian
      • Kava
      • Ginkgo
      • St John’s wort
    • The 4 most common classes of prescription medications with a potential for interaction accounted for 94% of the potential clinically significant interactions.
      • Antithrombotic medications
      • Sedative
      • Antidepressant drugs
      • Antidiabetes drugs

    The bottom line?
    No patient was harmed seriously from any interaction.

    It’s still a good idea to include a list of your supplements with your prescription drugs when you go to the doctor.

    3/22/08 20:31 JR

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