The C.A.M. Report
Complementary and Alternative Medicine: Fair, Balanced, and to the Point
  • About this web log

    This blog ran from 2006 to 2016 and was intended as an objective and dispassionate source of information on the latest CAM research. Since my background is in pharmacy and allopathic medicine, I view all CAM as advancing through the development pipeline to eventually become integrated into mainstream medical practice. Some will succeed while others fail. But all are treated fairly here.

  • About the author

    John Russo, Jr., PharmD, is president of The MedCom Resource, Inc. Previously, he was senior vice president of medical communications at, a complementary and alternative medicine website.

  • Common sense considerations

    The material on this weblog is for informational purposes. It is not medical advice or counsel. Be smart, consult your health professional before using CAM.

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    Omega-3 and advanced prostate cancer

    Researchers from the University of California, San Francisco report that omega-3 protects against advanced prostate coancer.

    And there’s a COX-2 genetic connection.

    First, the details.

    • 466 men with aggressive prostate cancer were compared to 478 age- and ethnicity-matched controls.
    • Diet was assessed using a food frequency questionnaire.
    • DNA was assessed to identify a COX-2 genetic connection.

    And, the results.

    • Increasing intake of omega-3 fatty acids was significantly associated with a decreased risk of aggressive prostate cancer.
    • The protective effect was even stronger in men who carried the COX-2 rs4647310 gene — a risk factor for prostate cancer.

    The bottom line?
    The authors concluded, “Dietary long chain omega-3 polyunsaturated fatty acids appear protective for aggressive prostate cancer.”

    In addition, the increased risk of prostate cancer associated with the COX-2 rs4647310 gene was “essentially reversed by increasing omega-3 fatty acid intake by a half a gram per day,” Dr. John Witte said in a Medscape interview.

    A recent review nutrition and prostate cancer concurs regarding the benefits of omega-3 as it relates to prostate cancer risk. Now, we have data on the risk of advanced prostate cancer.

    3/27/09 20:01 JR

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