Initial study of Zyflamend for prostate cancer

Laboratory research suggests that Zyflamend — an extract containing 10 herbs — decreases prostate cancer growth.

Now, researchers from the Center for Holistic Urology at Columbia University Medical Center and New York-Presbyterian Hospital/Columbia are starting a systematic evaluation in patients.

First, the details as reported by

  • 23 men with high-grade prostatic intraepithelial neoplasia (tumor formation) and an increased risk of developing prostate cancer were assigned to a treatment group for 18 months.
    • Zyflamend taken 3 times daily by mouth
    • Zyflamend taken 3 times daily by mouth + other dietary supplements

And, the results.

  • Zyflamend taken 3 times daily for up to 18-months was well tolerated.

The bottom line?
Dr. Aaron Katz concluded, “Since we know that men with high-grade prostatic intraepithelial neoplasia have an increased risk for developing prostate cancer, new strategies formulated to decrease cancer risk, prevent or delay surgery, and improve quality of life, will be greatly beneficial.”

These results are an important first step. Next, I assume, will be to design a study in men to detect any effect of Zyflamend on the development or progression of the tumor.

Memorial Sloan-Kettering Cancer Center has a review of Zyflamend.

The 10 herbals in this formulation include…

  • Ocimum sanctum (Holy basil) leaf
  • Curcuma longa (Turmeric) rhizome
  • Zingiber officinale (Ginger) rhizome
  • Camellia sinensis (Green tea) leaf
  • Rosemarinus officinalis (Rosemary) leaf and essential oil
  • Polygonum cuspidatum (Hu Zhang) root
  • Coptis chinensis (Chinese goldthread) root
  • Berberis vulgaris (Barberry) root
  • Origanum heracleoticum (Oregano) leaf
  • Scutellaria baicalensis (Scullcap) root

5/24/09 15:54 JR

Hi, I’m JR

John Russo, Jr., PharmD, is president of The MedCom Resource, Inc. Previously, he was senior vice president of medical communications at, a complementary and alternative medicine website.