Inflammatory Bowel DiseaseOmega-3 Fatty Acids

Omega-3 not effective for Crohn’s disease, again

 That’s the conclusion from this Cochrane review.

First, the details.

  • A search of the literature resulted in 6 studies eligible for inclusion.

And, the results.

  • Although some of studies reported a significant benefit in maintaining remission, they were very different in design.
  • 2 large studies showed negative results.
  • No serious side effects were recorded.
  • But there was a significantly higher rate of diarrhea and symptoms of the upper gastrointestinal tract associated with taking omega-3 fatty acids.

The bottom line?
Omega-3 fatty acids are safe but the existing data “do not support routine maintenance treatment of Crohn’s disease with omega 3 fatty acids.”

An earlier Cochrane review based on 4 studies came to the same conclusion.

1/23/09 21:30 JR

Hi, I’m JR

John Russo, Jr., PharmD, is president of The MedCom Resource, Inc. Previously, he was senior vice president of medical communications at, a complementary and alternative medicine website.