The C.A.M. Report
Complementary and Alternative Medicine: Fair, Balanced, and to the Point
  • About this web log

    This blog ran from 2006 to 2016 and was intended as an objective and dispassionate source of information on the latest CAM research. Since my background is in pharmacy and allopathic medicine, I view all CAM as advancing through the development pipeline to eventually become integrated into mainstream medical practice. Some will succeed while others fail. But all are treated fairly here.

  • About the author

    John Russo, Jr., PharmD, is president of The MedCom Resource, Inc. Previously, he was senior vice president of medical communications at, a complementary and alternative medicine website.

  • Common sense considerations

    The material on this weblog is for informational purposes. It is not medical advice or counsel. Be smart, consult your health professional before using CAM.

  • Recent Posts

  • Recent Comments

    Antioxidants and the risk of heart disease in diabetes

     Researchers from across the Commonwealth studied the potential value of antioxidants in preventing heart complications in people with diabetes.

    First, the details.

    • 1276 adults with type 1 or type 2 diabetes and an ankle brachial pressure index (ABPI) of 0.99 or less but no symptomatic cardiovascular disease were studied.
      • ABPI measures blood pressure in the legs to detect peripheral vascular disease.
    • Participants were randomly assigned to 4 groups.
      • Aspirin 100 mg + antioxidant
      • Aspirin 100 mg + placebo
      • Placebo + antioxidant
      • Placebo + placebo
    • The antioxidant capsule contained alpha-tocopherol 200 mg, ascorbic acid 100 mg, pyridoxine hydrochloride 25 mg, zinc sulphate 10 mg, nicotinamide 10 mg, lecithin 9.4 mg, and sodium selenite 0.8 mg.
    • Neither the researchers nor patients knew the treatment given — double-blind.

    And, the results.

    • There was no evidence that any of the treatments protected from any of the following complications.
      • Death from heart disease or stroke
      • Non-fatal heart attacks or stroke
      • Amputation above the ankle for limb ischemia

    The bottom line?
    The authors concluded there was “no evidence to support the use of either aspirin or antioxidants in the primary prevention of cardiovascular events and mortality in people with diabetes.”

    “Primary prevention” refers to treating someone to prevent a complication they have never had. In the case of aspirin, we know it’s effective for lowering the risk of secondary occurrences of cardiovascular complication in people (not just diabetics) with symptomatic peripheral arterial disease.

    10/17/08 09:20 JR

    Leave a Comment

    You must be logged in to post a comment.