Popular weight loss supplements reviewed
A couple of PharmDs from Ohio have published a review of 16 weight loss supplements (and 1 drug) used to help shed excess girth.
I’ll give just the bottom line on each supplement here.
Bitter orange (Citrus aurantium)
- Little evidence supporting its use.
- Can elevate heart rate and blood pressure.
- Those with a history of cardiovascular disease should avoid it.
Chitosan
- Scientific evidence does not support using this fat blocker.
Chromium (Chromium picolinate)
- Yes, this trace element aids in insulin secretion.
- Few studies support its use as a weight loss aid.
- A recent, comprehensive review concluded that it does not alter body composition.
Conjugated linoleic acid (CLA)
- Not supported for weight loss.
- It might help attenuate weight gain in patients with a dietary deficiency of CLA
Fiber
- Although claimed to increase satiety, there is little evidence to support this claim.
Green tea (Camellia sinensis)
- Green tea products contain varying amounts of caffeine, which has a mild diuretic effect.
- Some may perceive this as weight loss, but it’s only a transient loss of sodium and water.
Guar gum (Cyamopsis tetragonolobus)
- It’s a source of soluble dietary fiber.
- Insufficient evidence to recommend is for weight loss.
Guarana (Paullinia cupana)
- Not much support for using it alone.
- Most studies combined it with ephedra.
- Probably should be avoided due to adverse effects on the central nervous system.
Hoodia
- Popular, but little scientific support.
- See an earlier post for more information.
Hydroxycitric acid (Garcinia cambogia)
- Appears to be safe.
- Proof of weight loss in humans is lacking.
L-Carnitine
- One study, which did not report positive results.
- Watch for nausea or diarrhea.
Natural licorice
- No evidence of weight loss.
Usnic acid
- No evidence of effectivness
- A report of fulminate liver failure, make this a bad choice for weight control
White kidney bean extract (Phaseolus vulgaris)
- Advertised as a “carb blocker” that reduces the rate that starch is converted to sugar in the digestive process, thus reducing caloric intake.
- One study showed a positive modest response in a decrease in body mass index.
Willow bark
- No studies on weight loss.
- One report of a severe reaction in a young person who was allergic to aspirin.
Yohimbine (Pausinystalia yohimbe)
- The 2 studies available published opposite results.
- High blood pressure, anxiety, and agitation are side effects.
The bottom line?
The article provides useful background information. Read it all for greater detail
5/19/08 19:42 JR