The C.A.M. Report
Complementary and Alternative Medicine: Fair, Balanced, and to the Point
  • About this web log

    This blog ran from 2006 to 2016 and was intended as an objective and dispassionate source of information on the latest CAM research. Since my background is in pharmacy and allopathic medicine, I view all CAM as advancing through the development pipeline to eventually become integrated into mainstream medical practice. Some will succeed while others fail. But all are treated fairly here.

  • About the author

    John Russo, Jr., PharmD, is president of The MedCom Resource, Inc. Previously, he was senior vice president of medical communications at, a complementary and alternative medicine website.

  • Common sense considerations

    The material on this weblog is for informational purposes. It is not medical advice or counsel. Be smart, consult your health professional before using CAM.

  • Recent Posts

  • Recent Comments

    Review: EPA to treat depression

    Researchers at the New York State Psychiatric Institute, in New York City, used a meta-analysis to test the hypothesis that eicosapentaenoic acid (EPA) is the effective component in omega-3 fatty acid treatment of major depressive episodes.

    First, the details.

    • 15 studies involving 916 participants were included.
    • A depressive episode was the primary complaint (with or without comorbid medical conditions).

    And, the results.

    • Supplements containing at least 60% EPA showed significant benefit on depression scores vs supplements with less than 60% EPA.
      • Treatment duration or patient age did not affect the results.
    • Supplements with EPA less than 60% were ineffective.
    • Improvement was associated with a dose of EPA that was greater than docosahexaenoic acid (DHA), within the range of 200 to 2,200 mg/day of EPA.

    The bottom line?

    The authors concluded, “Supplements containing EPA at least 60% of total EPA + DHA, in a dose range of 200 to 2,200 mg/d of EPA in excess of DHA, were effective against primary depression.

    So, now you have guidelines for selecting an omega-3 supplement.

    10/27/11 20:18 JR

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