Researchers from the Cleveland Clinic, in Ohio have reviewed what we know about the effects of omega-3 fatty acids on triglyceride levels and in preventing arrhythmias, reducing inflammation, inhibiting platelet aggregation, and lowering blood pressure.

Here are the highlights.

  • The American Heart Association recommends that healthy people consume fatty fish at least twice a week.
  • People with coronary artery disease should take 1 gram of eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) per day.
  • A formulation of EPA + DHA is available by prescription and approved to treat triglyceridemia in excess of 500 mg/dL — the dose is 2 to 4 capsules per day.
  • Experts generally believe that omega-3 fatty acids reduce arrhythmic events.
    • But, we lack clear evidence of their clinical effectiveness.
  • Overall, omega-3 fatty acids have minimal side effects.

Reviewers from South University in Savannah, Georgia have also contributed a review article.

6/18/09 18:23 JR

Hi, I’m JR

John Russo, Jr., PharmD, is president of The MedCom Resource, Inc. Previously, he was senior vice president of medical communications at, a complementary and alternative medicine website.