Nervoheel N is a homeopathic preparation used to treat psychosomatic disorders, climacteric neurosis, and emotional distress

In this study, it’s reported to be as effective as lorazepam (Ativan).

First, the details.

• 248 patients with insomnia, distress, anxieties, restlessness or burnout and similar nervous conditions (?mild nervous disorders?) were treated with Nervoheel N or lorazepam at recommended doses for up to 4 weeks.
• Dose variations were allowed if in the patient’s best interest.
• Treatment effects were evaluated by the practitioner in dialogue with the patient at the start of treatment, after 2 weeks and after maximally 4 weeks.
• There was no attempt to randomly assign patients to treatment or conceal the treatment given.

And, the results.

• Both treatment groups reported significant symptomatic improvements.
• Differences between the groups were not significant.
• Both treatments were well tolerated, with few adverse events and good self-assessed tolerability.

The bottom line?
The authors conclude, “In patients who opt for a homeopathic treatment regimen for the short-term relief of mild nervous disorders, the effects of Nervoheel N are non-inferior to those of lorazepam.”

But wait.

Ativan is FDA-approved only for the management of anxiety or anxiety associated with depressive symptoms. It is not approved to treat insomnia, distress, restlessness, or burnout and similar “nervous conditions.”

Was this a fair comparison?

The study is open to additional criticism.

• Broad, poorly defined conditions were treated.
• Lack or random assignment of treatment
• No blinding of the patients or doctors to the treatment
• Lack of independent assessment of outcomes.

Except for the last criticism, this study could have been better for little if any increase in cost.

11/23/07 20:23 JR