Epilepsy/SeizuresVitamin D

The risk of vitamin D deficiency in people with epilepsy

Research presented during the American Epilepsy Society 61st Annual Meeting shows that almost half of all people with epilepsy are vitamin D deficient.

First, the details.

  • 25-hydroxy-vitamin D blood levels were measured in 285 men and women with a seizure disorder.
  • They were then treated with 1 capsule of 50,000 IU of vitamin D2 per week for 8 weeks, and rechecked.

And, the results.

  • 45% of epilepsy patients — 45% of men and 44% of women — were vitamin D deficient.
  • Those who took the vitamin D experienced improvement.

The bottom line?
Vitamin D deficiency potentially increases the risk for a wide variety of conditions, including osteoporosis, autoimmune disease, cancer, cardiovascular disease, and infectious disease. It’s also been reported in children with epilepsy.

In a Medscape interview, Dr. Ioannis Karakis from Boston University School of Medicine in Massachusetts states that antiepileptic medicine can affect vitamin D metabolism, leading to the deficiency. In addition, lifestyle changes that limit sun exposure and physical activity can lower bone-mineral density.

Vitamin D supplements are recommended for people with epilepsy.

12/7/07 19:31 JR

Hi, I’m JR

John Russo, Jr., PharmD, is president of The MedCom Resource, Inc. Previously, he was senior vice president of medical communications at www.Vicus.com, a complementary and alternative medicine website.