The C.A.M. Report
Complementary and Alternative Medicine: Fair, Balanced, and to the Point
  • About this web log

    This blog is intended as an objective and dispassionate source of information on the latest CAM research. Since my background is in pharmacy and allopathic medicine, I view all CAM as advancing through the development pipeline to eventually become integrated into mainstream medical practice. Some will succeed while others fail. But all are treated fairly here.

  • About the author

    John Russo, Jr., PharmD, is president of The MedCom Resource, Inc. Previously, he was senior vice president of medical communications at www.Vicus.com, a complementary and alternative medicine website.

  • Common sense considerations

    The material on this weblog is for informational purposes. It is not medical advice or counsel. Be smart, consult your health professional before using CAM.

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    Effects of low vitamin D levels on fatty infiltration in muscle

    Vitamin D insufficiency has now reached epidemic proportions and so has the research on its wide ranging effects.

    Here’s the latest from researchers in Los Angeles and Montréal.

    First, the details.

    • In 90 women 16 to 22 years, body fat distribution and blood levels of vitamin D (25OHD) were measured.
    • All were from California and have lots of opportunity for sun exposure.

    And, the results.

    • Approximately 59% of the women were vitamin D insufficient (29 ng/mL or less).
      • Of these women 24% were deficient (20 ng/mL or less).
    • Lower vitamin D levels were significantly associated with a higher percent of muscle fat.
    • In contrast, there was no relationship between vitamin D blood levels and thigh muscle area.
    • The amount of abdominal fat did not affect the relationship between vitamin D and muscle fat.
    • Percent muscle fat was significantly lower in women with normal serum vitamin D blood levels than in women with insufficient and deficient levels.

    The bottom line?

    the authors concluded that vitamin D insufficiency is associated with increased fat infiltration in muscle in healthy young women.

    These finding are important because skeletal muscle is crucial for about 80% of blood sugar disposal in the human body. Emerging evidence suggests that fat accumulation in skeletal muscle may be a major cause of insulin resistance and diabetes.

    3/15/10 20:35 JR

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